Process analytical technology mechanisms in biologics manufacturing
نویسندگان
چکیده
منابع مشابه
Process Analytical Technology for Advanced Process Control in Biologics Manufacturing with the Aid of Macroscopic Kinetic Modeling
Productivity improvements of mammalian cell culture in the production of recombinant proteins have been made by optimizing cell lines, media, and process operation. This led to enhanced titers and process robustness without increasing the cost of the upstream processing (USP); however, a downstream bottleneck remains. In terms of process control improvement, the process analytical technology (P...
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ژورنال
عنوان ژورنال: Chemie Ingenieur Technik
سال: 2018
ISSN: 0009-286X
DOI: 10.1002/cite.201855302